Population genomics · Quantitative biology

From genomes to biological stories.

Von Genomen zu biologischen Geschichten.

Population genomics, selection signatures, and reproducible research in avian systems.

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Based in Australia
Open to collaboration

Lead project · 01

FCG Goose Population Genomics

Selection signatures across domesticated goose populations

Within-population homozygosity

426 samples7.36M variants38 autosomes
−log10(p)
1510152025303538
candidate region

Schematic interface using verified project scale; locus coordinates are intentionally omitted until publication review.

01

FCG
RESEARCH
PORTFOLIO

01 · Featured research

An integrated view of selection

The project combines four complementary signals to identify genomic regions that distinguish Fengcheng Grey Goose from domestic comparison populations.

01

Research question

Which genomic regions carry consistent evidence of selection, and how do their haplotype patterns differ across breeds?

02

Analytical framework

Genome-wide scans are reconciled through provenance-aware overlap, followed by pathway enrichment and reference-anchored haplotype analysis.

03

Candidate portfolio

Priority and provisional regions are tracked separately so that strength of evidence remains visible.

Current candidate dossier

Evidence
01AREG–EREG / IL8

Fst · GWAS · XP-EHH

Priority
02CD4 / MLF2

zHP · GWAS · XP-EHH

Priority
03CAV1 / CAV2

Fst · GWAS · XP-EHH

Gene cluster
04RUNX2

zHP · GWAS · XP-EHH

Provisional

02 · Methods

A reproducible research practice

Each stage is designed to remain traceable—from sample selection and coordinate locking to final figures and audit tables.

01

zHP

Within-population homozygosity

02

Fst

Population differentiation

03

XP-EHH

Cross-population selection

04

GWAS

Trait association

03

RESEARCH
EXPERIENCE

03 · Experience

Building reliable genomic workflows

Current experience is centred on population-scale data, selection scans, candidate-locus synthesis, and publication-ready scientific visualisation.

01

Selection scans

Genome-wide zHP, Fst, XP-EHH, and GWAS workflows with explicit thresholds and quality checks.

02

Haplotype analysis

FCG-anchored phased haplotypes, within-breed clustering, distance summaries, and exact-region gene structures.

03

Scientific communication

Publication figures, provenance tables, GO/KEGG synthesis, and auditable reports for complex analyses.

Project timeline

FCG population genomics

Formal integration of selection scans, enrichment, candidate-locus review, and fine mapping.

Candidate validation

AREG–EREG/IL8, CD4/MLF2, CAV1/CAV2, and provisional RUNX2 regions.

Publication synthesis

Consolidating figures, biological interpretation, and a reproducible methods record.

04 · Research notes

Methods, decisions, and lessons learned

Short field notes will document why analytical choices were made—not only what was run.

NOTE · 01

Reference matters

Why FCG-anchored haplotypes answer a different question from global REF/ALT encoding.

NOTE · 02

Exact regions

How coordinate locks, no-overwrite rules, and preflight checks prevent silent analysis drift.

NOTE · 03

Evidence layers

Separating priority, clustered, and provisional candidate loci before biological interpretation.